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Despite being a widespread medical condition, the precise cause behind polycystic ovarian disease is not yet fully understood. Environmental and genetic factors possibly combine to cause this problem. That means patients usually have some sort of genetic predisposition to this problem, but it is also triggered by something in the environment. So, let’s take a look at the factors that increase or contribute to the risk of the syndrome: • Genetics: If a family member has PCOS, you are at risk as well. However, the problem might vary considerably along family lines. Moreover, research indicates that daughters of PCOS patients are eight times more susceptible to diagnosis – a risk that grows significantly if the mother smoked at the time of pregnancy. • Utero Changes: Some studies indicate that the disease may develop in the womb. Pregnant PCOS patients had higher AMH levels compared to regular pregnant women. • Stress: Psychological stress may give rise to the symptoms of PCOS. Women may suffer from mood problems, like anxiety and depression, and even feel suicidal. Stress also leads to chronic inflammation, which directly contributes to PCOS symptoms. • Weight Gain/Loss: Difficulty losing or gaining weight are two indicators of PCOS. Numerous doctors associate weight issues with PCOS. Losing only 7 percent of body weight can reduce symptoms like irregular periods considerably. • Sleep Apnea: Sleep apnea may be a sign of PCOS. The condition reduces insulin resistance and glucose intolerance, worsening the symptoms and increasing complications.