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Home treatments are unable to make a cyst disappear completely. They are geared more towards treating symptoms and managing pain. That being said, some effective strategies for large ovarian cyst include over-the-counter medication like ibuprofen and other NSAIDs; regular stretching and exercise; massage of the thighs, stomach, lower back, and buttocks; relaxation techniques for reducing anxiety and stress; heat; weight loss, and dietary changes. All the while, the patient’s doctor must keep a close eye on changes occurring in the tumor.