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Yes, medicines can temporarily reduce the production and development of sperm in men. These include certain antibiotics, anti-androgens, anti-inflammatory drugs, anti-psychotics, corticosteroids, anabolic steroids and methadone. While it may be medically important for a man to take such drugs, he should consult a doctor for better alternatives if he is prone to infertility. Why? Because most of these medicines temporarily reduce healthy sperm production, usually as long as they are taken. If you stop taking them, the sperm count goes back to normal in a few days. Discuss the same in detail with your doctor.