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Anaesthetic sprays containing numbing agents like prilocaine, lidocaine, and benzocaine may help with the problem of premature ejaculation. Make it a point of applying the spray on your penis 10 to 15 minutes before sex to delay the ejaculation process and reduce sensation. Speak to your doctor about your problem in detail, and depending on the severity of your condition, he/she will either prescribe over-the-counter medication or prescription-only sprays.