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Antidepressants often provide relief from various depression symptoms. But there may be side effects. While some are manageable, others may cause problems in your daily life. The reaction varies from person to person, but a few of the side effects are weight gain, nausea, dizziness, anxiety, dry mouth, sleep problems, reduced sex drive, constipation, blurred vision, and tiredness. Patients may experience several of these symptoms together or just one.